Pharmaceutics 1 BIPH 3219

Course description:

This course covers information resources in pharmacy and pharmaceutical sciences, and drug literature. It provides a complete idea on prescription, posology, compatibility and the basic principles of compounding and dispensing of drug delivery systems. It provides basic information about classification, definition and route of administration, general advantages, disadvantages and formulation of pharmaceutical solutions for oral administration, pharmaceutical disperse systems (suspensions, emulsions, creams, ointments, pastes, lotions, gels and related formulations), vaginal and rectal dosage forms, and respiratory dosage forms.

Course Aims:

To introduce students to, and provide a broad based knowledge and understanding of :
  • The types and uses of pharmaceutical solutions as oral drug delivery systems
  • The advantages and disadvantages of pharmaceutical solutions as oral drug delivery systems
  • The formulation considerations for orally administered pharmaceutical solutions.
  • The physical stability of pharmaceutical disperse systems.
  • The advantages and disadvantages pharmaceutical disperse systems.
  • Formulation considerations for pharmaceutical disperse systems.
  • Considerations for the manufacture of pharmaceutical disperse systems.
  • Description of rectal, vaginal and respiratory dosage forms and the rationale for their use.
  • Formulation strategies for suppositories, pessaries and related products that are specifically designed for administration to the rectum or vagina.
  • The advantages and disadvantages of rectal, vaginal and respiratory dosage forms.
  • Considerations for the manufacture of rectal, vaginal and respiratory dosage forms.

Course outcomes:

Upon successful completion of this course students will be able to:  
  • Define the various types of oral and topical liquid dosage forms.
  • List the advantages and disadvantages of using liquid dosage forms in extemporaneous compounded prescriptions and in patient therapy.
  • Compare and contrast the different pharmaceutical solutions for oral drug delivery systems.
  • Evaluate and select a proper solvent and delivery system for a given solute, purpose, and/or patient population.
  • Differentiate between the various types of pharmaceutical disperse systems on the basis of physical and chemical properties.
  • Describe the methods to incorporate (an) active ingredient(s) into pharmaceutical disperse systems.
  • Explain the difference between different pharmaceutical disperse systems.
  • List advantages and disadvantages of administering drugs in pharmaceutical disperse systems.
  • Compare and contrast rectal, vaginal and respiratory dosage forms in terms of physical appearance, size, and shape.
  • Describe the advantages and disadvantages of rectal, vaginal and respiratory dosage forms.
  • Identify and explain physiologic factors that influence the drug absorption from rectal, vaginal and respiratory dosage forms.
  • Describe the methods of rectal, vaginal and respiratory dosage forms preparation.
  • Generate a listing of key counseling points a pharmacist should share with the patient prescribed a drug in a suppository/insert/stick drug delivery system.