Pharmacology & Toxicology 2 Lab BIPH 5147

Course description:

This course covers the basic concepts of Cardiovascular Pharmacology to students & will investigate aspects of muscle function and drug effects in diverse isolated tissues and whole animal preparations including:
This course will introduce the basic concepts of CNS Pharmacology, including experimental Parkinsonism, Analgesic effect of some drugs, local anesthetic agents and induction of physical dependence using morphine.

Course Aims:

Upon successful completion of this course, participants will be able to:
  • Handling and applications of different species and strains of animals, transgenic animals. Anesthesia and euthanasia of experimental animals. Maintenance and breeding of laboratory animals. Limitations of animal experimentation and alternate animal experiments. 
  • Extrapolation of in vitro data to preclinical and preclinical to humans.
  • Uses a small mammal, rabbit & albino rats to investigate the actions of various pharmacological agents on the arterial blood pressure.

Course outcomes:

Upon successful completion of this course students will be able to:  
  • Learn Cardiac muscle function in the mammalian atria and heart.
  • Know vascular tissue (Rat coronary artery & rabbit blood pressure).
  • Know the effects of drugs on the isolated rabbit heart, using a Langendorff apparatus.