Course description:
The course covers the Molecular effects of drugs at receptor sites, ion channels, signal transduction, action of drugs on the autonomic and central nervous systems, cardiovascu
lar system, respiratory and gastrointestinal tracts, kidney, chemotherapeutic agents, anti-cancer agents, drugs acting on the endocrines.. Basic toxicological principles as applied in the study / detection of potentially harmful chemicals, with relevance in drug design and therapy, forensic medicine, and environmental toxicology. Incidence of poisoning, mechanisms of cellular toxicity, factors modifying toxic effects, relevance for adverse drug reactions. Mutagenicity and carcinogenicity. Management of the poisoned patient.