Pharmaceutical Chemistry 2 BIPH 3224

Course description:

The course is a continuation of the Pharmaceutical Chemistry I. The course covering the following  general properties of the drugs effecting on central nervous system and general anesthetic drugs Sedative and hypnotics Tranquilizers, Neuroleptics, Antidepressants: Tricyclic Antidepressants: MAO Inhibitors, Antidepressants: Serotonin reuptake inhibitors, Psychomimetics, analeptics, Skeletal muscle relaxants, Antiepileptic’s, Narcotic analgesics, Antitussive-expectorants Nonnarcotic analgesics and Local anesthetics.

Course Aims:

  • Equip students with knowledge about chemistry (properties, source/synthesis, reactivity, and detectability) of drugs and auxiliary substances. 
  • Introduce the major syntheses, structure-activity relationship, analytical methods, metabolic pathways of further anti-infective, antivirals, anti-parasitic and anti-helminthic, antifungals, and antineoplastic agents, as well as disinfectants and major auxiliary compounds.

Course outcomes:

Upon successful completion of this course students will be able to:  
  • Discuss Structure, Stereochemistry, Nomenclature, Synthesis of specified drugs, mode of action, Structure Activity Relationships (if any) uses and Physicochemical properties of the following classes of drugs: anti-infective, antivirals, anti-parasitic and anti-helminthic, antifungals, and antineoplastic agents.
  • Recognize the physicochemical properties of diverse drugs. 
  • Specify the methods of synthesis, as well as the methods of qualitative and quantitative analysis of diverse drugs. 
  • Describe the design of diverse drugs. 
  • Discuss the mechanism of action, therapeutic use, and adverse effects of various drugs.