Pharmaceutical Organic Chemistry 1 BIPH 2311

Course description:

This course covers the following classes of compounds with regard to IUPAC nomenclature, nature of bond, polarity, strengths, pKa, etc. sources, methods of
preparation, structure and physical properties(Structure property relationships), and
general reactions: the Aliphatic Compounds Including Alicyclic: Hydrocarbons, halogen alcohols, ethers, thiols and thioethers, carbonyl and  thiocarbonyl compounds, Amines, imines, amides, nitro, Sulphoxides and sulphones. Also it will cover Aromatic Compounds, and Combination functional and Multiple functional groups and property changes. This course cover the fundamentals of organic chemistry  which will establish student for other organic chemistry related courses such as organic chemistry 2, Phytochemistry and Pharmacology. The course covers the following topics: the basic concepts of bonding and molecular structure, Polar Covalent Bonds; Acids and Bases, Chemistry of Saturated hydrocarbons: Alkanes and Their Stereochemistry, Cycloalkanes and Their Stereochemistry and conformation, Stereochemistry at Tetrahedral Centers, An Overview ofOrganic Reactions, Alkenes and Alkynes, the chemistry of Alkyl halides, their important reactions NucleophilicSubstitutions (SN1,SN2)and Eliminations (E1, E2) reactions.AlcoholsandPhenols and their reactions. andThiols,  Ethers and Sulfides.

Course Aims:

  • To introduce students to the basic concepts in organic pharmaceutical chemistry.
  • To integrate pharmaceutical applications into basic organic chemistry.

Course outcomes:

Upon successful completion of this course students will be able to:  
  • Illuminate relevance & significance of Organic Chemistry to Pharmaceutical Sciences. 
  • Clarify basic principles concepts of organic chemistry. 
  • Explain basic functional groups & IUPAC Nomenclature of Organic Compounds.
  • Confirm of purity of pharmaceutical organic compounds 
  • Clarify Isomerism & apply that knowledge in understanding the Structure Property Relationship.